Rare mutations in apoptosis related genes APAF1, CASP9, and CASP3 contribute to human neural tube defects
نویسندگان
چکیده
منابع مشابه
Association Between a Polymorphism in CASP3 and CASP9 Genes and Ischemic Stroke
OBJECTIVE To investigate whether the polymorphisms of CASP3 gene (rs4647602, intron A/C and rs1049216, UTR C/T) and CASP9 gene (rs1052576, Gln/Arg G/A and rs1052571, Ser/Val T/C) were associated with the development, and clinical severity of ischemic stroke and functional consequences after stroke. METHODS Genomic DNA from 121 ischemic stroke patients and 201 healthy control subjects were ext...
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ژورنال
عنوان ژورنال: Cell Death & Disease
سال: 2018
ISSN: 2041-4889
DOI: 10.1038/s41419-017-0096-2